ea0025oc5.6 | Reproduction and fetal programming | SFEBES2011
Pope Madeleine
, Lambertucci-Bonnett Julien
, McGonnell Imelda
, Fowkes Robert
, Russell Claire
Exposure to a range of environmental endocrine disrupting chemicals is associated with birth defects in several species. High levels of oestrogen, or compounds acting as oestrogen mimics (such as alkyl phenols and pesticides) can alter gene expression and cause sex reversal in fish. In the current study, we use the versatile Zebrafish (Danio rerio) to examine the effect of embryonic exposure to 17β-estradiol (E2) on the development of brain asymmetry and...